Cystic Fibrosis Female Reproductive System
Cystic fibrosis female reproductive system. Cystic fibrosis is an inherited disease characterized by an abnormality in the glands that produce sweat and mucus. 97 percent of male CF patients and 20 percent of females are infertile. Signs and symptoms may include salty-tasting skin.
As health improves for people with cystic fibrosis CF women are increasingly living into their reproductive years and into menopause. Irregular menstrual periods. Thick secretions in the sperm canal can block sperm from getting through.
The vast majority of men with CF are infertile due to obstructive azoospermia. Delayed sexual development. Cystic fibrosis is an autosomal recessive genetic disorder that generally affects the pulmonary and digestive systems is most prevalent in caucasians of northern European descent and occurs in approximately 1 out of every 2500 live births National Institutes of Health 1995.
However women with CF are thought to generally be less fertile than women without CF. Although cystic fibrosis does not cause the absence of reproductive structures in females as it does in males the disease can reduce fertility in women. Multiple factors associated with CF contribute to an increased prevalence of testosterone deficiency which adversely affects muscle mass bone.
Women with CF have all the regular hormonal functions. Studies in mice with cystic fibrosis have shown some changes leading to reduced fertility including smaller ovaries smaller uteri irregular estrous cycles and decreased ovulation. Although most women with CF have normal hormonal function reproductive tracts and sexual development they also experience common reproductive health issues associated with CF.
And in males infertility. Cystic fibrosis does not seem to cause any changes to the physical structure of the female reproductive organs the way it does in males. CF patients often lack knowledge about sexual and reproductive health but desire increased attention to these aspects of their well-being 1 2.
There are many irregularly dilated endometrial glands. People with CF are living longer.
Cystic fibrosis CF has been linked to both obstructive male infertility and hypogonadism.
Symptoms that may be present due to CFs effects on the reproductive system include. Cystic fibrosis CF has been linked to both obstructive male infertility and hypogonadism. In the reproductive system the thickened secretions. W heezing or shortness of breath. Cystic fibrosis affects various organ systems in children and young adults including the respiratory system digestive system and reproductive system. People with CF are living longer. Fertility in women with cystic fibrosis. Cystic fibrosis CF is the most common genetic disorder among Caucasians with over 10 million people or one out of every 31 Americans - carrying the defective gene 1. Women are often able to conceive but may have decreased fertility because of thick cervical mucus blocking the entry of sperm.
Signs and symptoms may include salty-tasting skin. Irregular menstrual periods. Cystic fibrosis CF has been linked to both obstructive male infertility and hypogonadism. Women with CF have all the regular hormonal functions. Although most women with CF have normal hormonal function reproductive tracts and sexual development they also experience common reproductive health issues associated with CF. Symptoms that may be present due to CFs effects on the reproductive system include. There are many irregularly dilated endometrial glands.
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